Device Category Experience
PRECLINICAL STUDY CENTER FOR INNOVATIVE MEDICAL DEVICE
Brain computer interface field

Goldenwing is offering services for testing brain-computer interfaces (BCIs) in large animal models involving various medical devices that can facilitate research and development. These devices collectively aid in the exploration of BCIs' potential applications, therapeutic uses, and safety profiles in large animal models, facilitating advancements in the field.

1. Implantable Neural Interfaces

· Microelectrode Arrays: Devices that can record or stimulate neuronal activity, like the Utah Array or the Michigan Probe.

· Electrocorticography (ECoG) Grids: Placed on the cortex to monitor brain activity with high spatial resolution.

· Deep Brain Stimulators: Devices used to deliver electrical stimulation to specific brain regions for both therapeutic and research purposes.


2. Neurostimulation Devices

· Transcranial Magnetic Stimulation (TMS): Non-invasive technique to modulate neuronal activity, useful for understanding cortical connectivity.

· Transcranial Direct Current Stimulation (tDCS): A non-invasive method to alter neuronal excitability, applicable in BCI research.


3. Neural Signal Processing Systems

· Data Acquisition Systems: Devices that capture and digitize neural signals for analysis (e.g., Neuralynx or Tucker-Davis Technologies systems).

· Wireless Transmission Systems: Used to transmit neural signals without tethering, enabling free movement in animal models.


4. Behavioral Monitoring Devices

· Video Tracking Systems: For monitoring animal behavior in response to BCI stimuli.

· Force and Pressure Sensors: To measure the animal's interaction with devices controlled by BCIs.


5. Computational Platforms

· Real-time Signal Processing Software: Platforms for analyzing neural data in real-time (e.g., MATLAB, LabVIEW).

· Machine Learning Algorithms: For decoding neural signals and improving BCI responsiveness.


6. Surgical Instruments

· Micro-manipulators: For precise placement of electrodes in the brain.

· Biopsy Tools: For taking samples and assessing tissue response to implants.


7. Biocompatible Coatings

· Coating Materials: Such as polyimide or parylene, to reduce inflammatory responses around implanted devices.


8. Wearable Sensors

· Electroencephalography (EEG) Caps: For non-invasive monitoring of brain activity.

· Functional Near-Infrared Spectroscopy (fNIRS): A technique to measure hemodynamic responses associated with neural activity.


9. Pharmacological Delivery Systems

· Intracranial Infusion Pumps: For delivering drugs to specific brain regions, studying the effects on neural activity and BCI performance.


10. Assessment and Imaging Devices

· Magnetic Resonance Imaging (MRI): For anatomical imaging and to assess the effects of BCIs on brain structure.

· Computed Tomography (CT) Scans: For evaluating changes post-implantation.


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